Chapter 7 참고문헌

  1. Strauss, D.G., G. Gintant, Z. Li, W. Wu, K. Blinova, J. Vicente, J.R Turner and P.T. Sager(2018). “Comprehensive In Vitro Proarrhythmia Assay (CiPA) Update from a Cardiac Safety Research Consortium/Health and Environmental Sciences Institute/FDA Meeting.”Therapeutic Innovation & Regulatory Science: 216847901879511.

  2. FDA(2017). Impact Story: Finding a Better Test for Predicting the Risk Drugs Pose to the Heart.https://www.fda.gov/drugs/regulatory-science-action/impact-story-finding-better-test-predicting-risk-drugs-pose-heart

  3. O’Hara, T., L. Viràg, A. Varró and Y. Rudy(2011). “Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation.” PLoS Computational BIology 7(5):e1002601.

  4. Li, Z., S. Dutta, J. Sheng, P. N. Tran. W. Wu, K. Chang, T. Mdlluli, D. G. Strauss and T. Colatsky(2017). “Improving the In Silico Assessment of Proarrhythmia Risk by Combinin hERG(Human Ether-a-go-go-Related Gene) Channel-Drug Binding Kinetics and Multichannel Pharmacology.”Circ Arrhythm Electrophysiol 10(2): e1004628.

  5. Dutta, S., K. C. Chang, K. A. Beattie, J. Sheng, P. N. Tran, W. Wu, M. Wu, D. G. Strauss, T. Colatsky and Z. Li(2017). “ Optimizaion of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment” Front Physiol 8:616.

  6. FDA(2019). “ Comprehensive in vitro Proarrhythmia Assay (CiPA) in silico model: R code used to perform uncertainty quantification for the CiPA in silico model”.

  7. Han, S., S. Han, K. S. Kim, H. A. Lee and D. S. Yim (2019). “Usefulness of Bnet, a Simple Linear Metric in Discerning Torsades De Pointes Risks in 28 CiPA Drugs.” Front Pharmacol 10: 1419.

  8. Vicente, J., L. Johannesen, M. Hosseini, J. W. Mason, P. T. Sager, E. Pueyo and D. G. Strauss (2016). “ Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Curent Block”. PLoS oNE 11(12): e0163619.

  9. Darpo, B., C. Benson, R. Brown, C. Dota, G. Feber, J. Ferry, V. Jarugula, J. Keirns, C. Ortemann-Renon, T. Pharm, S. Riley, N. Sarapa, M. Ticktin, W. Zareba and J. P. Couderc (2020). “ Evaluation of the Effect of 5 QT-Positive Drugs on the JTpeak Interval-An Analysis of ECGs from the IQ-CSRC Study.” J Clin Pharmacol 60(1): 125-139.

  10. Vicente, J., L., Johannesen, M. Hosseini, J. W. Mason, P. T. Sager, E. Pueyo and D. G. Strauss (2016). “ Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.” PLoS One 11(12):e0163619.